Actos (pioglitazone)

  • A diabetes medicine we will consider using if you have pre diabetes in the presence of inflammation and significant plaque
  • Better at reducing inflammation and improving insulin resistance than Glucophage (metformin), which is the typical first line diabetes
  • Reduces heart attacks and stroke deaths in diabetics
  • Preserves beta cell function resulting in an 81% reduction in risk of going on to develop diabetes when used in pre diabetic patients. Metformin does not preserve beta cell
  • Must be used cautiously in people with heart failure, osteoporosis and macular
  • Is currently expensive, but goes generic in 2011